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Published on: December 20, 2024
Perioperative management in children with sickle cell disease undergoing laparoscopic surgery
Claudio Sandoval1, Gustavo Stringel, M Fevzi Ozkaynak
1Department of Pediatrics, New York Medical College, Westchester Medical Center, Valhalla 10595, USA.
Insights
Laparoscopic surgery is safe for pediatric patients with sickle cell disease. Careful perioperative management, including transfusion guidelines and pulmonary care, can reduce complications like acute chest syndrome.
Area of Science:
- Pediatric Surgery
- Minimally Invasive Surgery
- Hematology
Background:
- Sickle cell disease (SCD) presents unique challenges for surgical management.
- Laparoscopic surgery offers potential benefits in terms of recovery and morbidity.
Purpose of the Study:
- To evaluate the safety and outcomes of laparoscopic surgery in children diagnosed with sickle cell disease.
- To identify key factors influencing perioperative management and complication rates.
Main Methods:
- A retrospective chart review analyzed 13 pediatric patients with SCD undergoing laparoscopic procedures.
- Data collected included surgical indications, perioperative care, operative details, complications, and hospital stay.
- All procedures were performed by a single pediatric surgeon.
Main Results:
- Indications included symptomatic cholelithiasis/cholecystitis (9), splenic sequestration (3), and hypersplenism/cholelithiasis (1).
- Median operative time was 150 minutes with a median hospitalization of 3 days.
- Four patients experienced postoperative complications: 2 with acute chest syndrome, 1 with abdominal pain (retained CBD stone), and 1 with priapism. All resolved with treatment.
Conclusions:
- Laparoscopic surgery is a safe and viable option for children with sickle cell disease.
- Meticulous perioperative management, transfusion protocols, and pulmonary care are crucial for minimizing complications, particularly acute chest syndrome.
Objective:
The aim of this study was to evaluate our experience with laparoscopic surgery in children with sickle cell disease.
Methods:
A retrospective chart review was performed to analyze the indication for surgery, perioperative management, surgical technique, complications, duration of hospitalization, and outcome. One pediatric surgeon performed all procedures.
Results:
Thirteen children underwent laparoscopic surgery for the following indications: symptomatic cholelithiasis/cholecystitis in 9; recurrent splenic sequestration in 3; and hypersplenism/symptomatic cholelithiasis in 1. The 7 boys and 6 girls had a median age of 7.8 years. Patients undergoing splenectomy only were younger than those undergoing cholecystectomy (median age, 3.6 years versus 11.5 years, respectively). Four children underwent endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy because of common bile duct dilatation and stones. Twelve patients received packed red blood cell transfusions prior to surgery. The median operative time was 150 minutes, and the median hospitalization was 3 days. Four patients suffered postoperative complications (2 with acute chest syndrome, 1 with recurrent abdominal pain, and 1 with priapism). The patient with abdominal pain was found to have a retained stone in the common bile duct, which was retrieved via endoscopic retrograde cholangiopancreatography and sphincterotomy. All complications resolved with medical management.
Conclusions:
Laparoscopic surgery is safe in children with sickle cell disease. Meticulous attention to perioperative management, transfusion guidelines, and pulmonary care may decrease the incidence of acute chest syndrome.
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