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CTX-m-3 beta-lactamase-producing Escherichia coli from Greece
A Mavroidi1, E Tzelepi, V Miriagou
1Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
Microbial Drug Resistance (Larchmont, N.Y.)
|May 11, 2002
Abstract:
An Escherichia coli clinical strain resistant to all beta-lactams except carbapenems was isolated in a Greek hospital. Analysis of beta-lactamase content by isoelectric focusing, PCR assays specific for various bla genes, and DNA sequencing showed that the strain produced TEM-1, a Citrobacter freundii AmpC-related cephalosporinase, and CTX-M-3. The blaCTX.M-3 gene was carried by a 120-kb plasmid that was readily transferable to a susceptible E. coli host.