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Streptococcus pneumoniae as an etiologic agent in infectious complications of pancreatic disease

Marianne Konkoly Thege1, István Pulay, Eszter Balla

  • 1Department of Bacteriology, National Center for Epidemiology B. Johan, Budapest, Hungary. ktmarianne@hotmail.com

Microbial Drug Resistance (Larchmont, N.Y.)
|May 11, 2002
PubMed

Insights

Streptococcus pneumoniae was identified in infectious complications of chronic pancreatitis in nine male patients. This bacterium, often sensitive to penicillin, was successfully treated with surgery and antibiotics.

Area of Science:

  • Microbiology
  • Gastroenterology
  • Infectious Diseases

Background:

  • Chronic pancreatitis is a complex condition often leading to infectious complications.
  • The role of specific bacterial pathogens in pancreatitis-associated infections requires further elucidation.

Purpose of the Study:

  • To investigate the presence and significance of Streptococcus pneumoniae in infectious complications of chronic pancreatitis.

Main Methods:

  • Systematic culturing of perioperative intra-abdominal samples from patients with chronic pancreatitis.
  • Identification of bacterial isolates, including Streptococcus pneumoniae.
  • Antimicrobial susceptibility testing for Streptococcus pneumoniae isolates.
  • Clinical case history analysis.

Main Results:

  • Streptococcus pneumoniae was identified in infectious complications in 9 out of 9 male patients.
  • In 80% of intra- or peripancreatic samples, S. pneumoniae was the sole identified pathogen.
  • The majority of S. pneumoniae isolates demonstrated penicillin sensitivity.
  • Patients with predisposing conditions like alcoholism and diabetes mellitus were observed.
  • All patients achieved cure following surgical intervention and antibiotic therapy.

Conclusions:

  • Streptococcus pneumoniae may be a significant causative agent in infectious complications of chronic pancreatitis.
  • Prompt diagnosis and appropriate treatment, including surgery and antibiotics, lead to favorable outcomes.
  • Further research into the specific role of S. pneumoniae in pancreatitis is warranted.

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