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A Rat Model of EcoHIV Brain Infection
Published on: January 21, 2021
Neuropsychiatric aspects of human immunodeficiency virus (HIV) infection
1Department of Psychiatry, Loyola University Medical Center, 2160 South First Avenue, #54, Maywood, IL 60153, USA. fferna@lumc.edu
Abstract:
Human immunodeficiency virus (HIV) infection with central nervous system (CNS) involvement causes a variety of psychiatric complications among a significant proportion of infected individuals. A cure for the fully developed AIDS related to HIV infection remains elusive, and HIV/AIDS is a leading cause of death among adults between the ages of 25 and 44. Life expectancy, however, has gradually increased over the years, resulting in a concern for a potential increase in the incidence of secondary psychiatric manifestations. Knowledge of the neuropathology of HIV-CNS dysfunction and familiarity with its clinical presentation can aid clinicians in a determination of the appropriate therapy inclusive of psychiatric care that may be useful for a specific individual in their treatment.
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