Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Negative affect and sensitization to pain.

Sabine A Janssen1

  • 1Division of Clinical and Health Psychology, Faculty of Social Sciences, Leiden University, The Netherlands. janssensa@fsw.leidenuniv.nl

Scandinavian Journal of Psychology
|May 15, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal evidence of mediodorsal thalamus-prefrontal circuit dysfunctions in clinical high-risk for psychosis: findings from a combined 7T fMRI, MRSI and sleep Hd-EEG study.

Molecular psychiatry·2025
Same author

Transcranial Focused Ultrasound Neuromodulation in Psychiatry: Main Characteristics, Current Evidence, and Future Directions.

Brain sciences·2024
Same author

High frequency transcranial magnetic stimulation increases slow-wave activity during subsequent sleep in older adults with cognitive complaints.

Brain stimulation·2024
Same author

Changes in electroencephalographic microstates between evening and morning are associated with overnight sleep slow waves in healthy individuals.

Sleep·2024
Same author

Natural Oscillatory Frequency Slowing in the Premotor Cortex of Early-Course Schizophrenia Patients: A TMS-EEG Study.

Brain sciences·2023
Same author

N-Acetylaspartate and Choline Metabolites in Cortical and Subcortical Regions in Clinical High Risk Relative to Healthy Control Subjects: An Exploratory 7T MRSI Study.

International journal of molecular sciences·2023
Same journal

Eight-Week Minimal Dose Training Reduces Premenstrual Syndrome Symptoms but Does Not Influence Coping Strategies: A Nonrandomized Study.

Scandinavian journal of psychology·2026
Same journal

A Randomized Controlled Trial of an iCBT Program to Reduce Infertility-Related Stress: A Novel Digital Approach.

Scandinavian journal of psychology·2026
Same journal

Exploring Emotional Abuse, Physical Abuse and Mobile Phone Dependence in Left- and Non-Left-Behind Adolescents: Roles of Self-Esteem, Social Anxiety, and Loneliness.

Scandinavian journal of psychology·2026
Same journal

Swedish SDQ Norms for Internalizing and Externalizing Problems in Preschoolers.

Scandinavian journal of psychology·2026
Same journal

Exploring Toxic Positivity, Shame, Emotional Exhaustion, and Job Withdrawal Intentions in the Workplace.

Scandinavian journal of psychology·2026
Same journal

Cognitive Testing Practices for Basic Military Training in the Nordic Countries: A Scoping Review.

Scandinavian journal of psychology·2026
See all related articles

Negative affect, or unpleasant emotions, can significantly influence pain perception. While adaptive in acute pain, chronic negative affect and hypervigilance can worsen pain and disability.

Area of Science:

  • Psychology
  • Neuroscience
  • Pain Research

Background:

  • Pain perception is strongly modulated by negative affect.
  • Understanding the interplay between emotions and pain is crucial for effective management.

Purpose of the Study:

  • To review theories linking negative affect and pain perception.
  • To discuss mechanisms through which negative affect influences pain.
  • To differentiate adaptive and maladaptive effects in acute versus chronic pain.

Main Methods:

  • Literature review of theories on negative affect and pain.
  • Analysis of proposed neurophysiological and psychological mechanisms.
  • Distinction between acute and chronic pain contexts.

Main Results:

Related Experiment Videos

  • Negative affect can increase or inhibit pain through various mechanisms.
  • Pain-inhibiting mechanisms include opioid release, blood pressure reactivity, and distraction.
  • Pain-increasing mechanisms involve reactivity, misattribution, hypervigilance, worry, and avoidance.

Conclusions:

  • Mechanisms influencing pain perception are adaptive in acute pain.
  • In chronic pain, negative affect can lead to sensitization, hypervigilance, and functional disability.
  • Long-term negative affect associated with pain has sensitizing and disabling effects.