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Related Experiment Videos

Coma and thyroid storm in apathetic thyrotoxicosis.

Michel W Ghobrial1, Edward B Ruby

  • 1Department of Endocrinology, Mercy Catholic Medical Center, Darby, PA, USA.

Southern Medical Journal
|May 15, 2002
PubMed
Summary
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A rare case of apathetic hyperthyroidism leading to thyroid storm and coma in an elderly woman was documented. Prompt antithyroid therapy led to a full recovery, highlighting the importance of recognizing this severe presentation.

Area of Science:

  • Endocrinology
  • Geriatric Medicine
  • Internal Medicine

Background:

  • Thyrotoxic crisis, a life-threatening condition, can present atypically in the elderly.
  • Apathetic hyperthyroidism is a variant characterized by blunted symptoms, often leading to delayed diagnosis.

Observation:

  • An 87-year-old woman presented with coma and was diagnosed with thyrotoxic crisis.
  • Her history included decreased mentation and apathy, with laboratory results confirming hyperthyroidism.

Findings:

  • The patient experienced a severe clinical course but ultimately recovered to her baseline state.
  • Antithyroid therapy normalized her laboratory values and improved her clinical condition.

Implications:

Related Experiment Videos

  • This case highlights a rare presentation of apathetic hyperthyroidism with thyroid storm and coma.
  • Recognizing and managing this severe endocrine emergency in the elderly is crucial for favorable outcomes.