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Naratriptan in the prophylaxis of cluster headache
1Harvard Medical School , Boston, Mass 02114, USA.
Headache
|May 15, 2002
Summary
Naratriptan effectively managed a severe cluster headache case refractory to other treatments. This finding suggests naratriptan as a potential option for difficult-to-treat cluster headache patients.
Area of Science:
- Neurology
- Pain Medicine
Background:
- Cluster headache is a debilitating neurological disorder.
- Refractory cases pose significant treatment challenges.
Observation:
- A 36-year-old male presented with severe, refractory cluster headaches.
- Standard treatments and parenteral sumatriptan/oxygen showed limited efficacy.
Findings:
- Scheduled parenteral dihydroergotamine provided temporary relief.
- Naratriptan 2.5 mg twice daily completely abolished headaches.
- Headaches recurred upon naratriptan discontinuation, with no observed side effects.
Implications:
- Naratriptan demonstrates potential as an effective treatment for refractory cluster headaches.
- This case highlights the need for exploring novel therapeutic options for severe cluster headache.