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Related Experiment Videos

Diffusion weighted MR imaging in acute stroke: the SGH experience.

L L Chan1, J B K Khoo, C H Thng

  • 1Department of Diagnostic Radiology, Singapore General Hospital, Singapore. gdrcll@sgh.com.sg

Singapore Medical Journal
|May 15, 2002
PubMed
Summary

Diffusion-weighted (DW) MRI is a fast and effective tool for detecting acute stroke, outperforming T2W scans. Public education is crucial to maximize the benefits of this advanced imaging for timely thrombolytic therapy.

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Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • Cerebrovascular accident (CVA) is a major cause of death and disability.
  • Diffusion-weighted (DW) magnetic resonance (MR) imaging shows promise for acute stroke detection and treatment evaluation.

Purpose of the Study:

  • To evaluate the utility of commercially available isotropic DW scans for acute stroke imaging.
  • To compare DW scans with conventional T2-weighted (T2W) scans in a clinical setting.
  • To identify the limitations of DW imaging in stroke diagnosis.

Main Methods:

  • Utilized rapid, sub-minute isotropic DW MRI scans.
  • Compared findings with conventional T2W scans.
  • Assessed performance in a busy clinical radiology unit.

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Main Results:

  • DW scans are well-suited for acute stroke patients, including those who are ill or restless.
  • DW imaging demonstrated superior sensitivity and lesion identification compared to T2W scans.
  • DW scans effectively differentiated acute ischemic lesions from chronic infarcts.
  • Potential pitfalls include evaluating small hyperacute posterior fossa strokes and venous infarcts.

Conclusions:

  • DW MRI is a powerful tool for diagnosing hyperacute strokes, enabling potential thrombolytic therapy.
  • A minority of patients qualified for the therapeutic window, highlighting a need for increased public awareness.
  • Enhanced public education is essential to realize the full value of DW imaging in thrombolytic programs.