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Related Experiment Videos

Some observations on blood microfilters.

R Buley, J Lumley

    Annals of the Royal College of Surgeons of England
    |November 1, 1975
    PubMed
    Summary

    New microfilters effectively reduce microemboli during blood transfusions, showing comparable performance to standard filters in preserving blood cell integrity and flow resistance.

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    Area of Science:

    • Biomedical Engineering
    • Hematology
    • Medical Device Technology

    Background:

    • Blood transfusions involve risks, including microemboli passage.
    • Standard filters primarily address macroemboli, leaving microemboli a concern.
    • Development of effective microemboli filters is crucial for transfusion safety.

    Purpose of the Study:

    • To compare the efficiency of three microemboli filters against a standard macroemboli filter.
    • To evaluate filters based on blood flow resistance and cellular damage.
    • To determine the optimal microfilter for transfusion applications.

    Main Methods:

    • Laboratory comparison of Pall Ultipor, Swank IL200, and Bentley Polyfilter (PF-127) microfilters.
    • Assessment against the Baxter BR10 standard filter.
    • Measurement of resistance to blood flow and damage to blood cellular elements.

    Main Results:

    • The Pall Ultipor microfilter demonstrated superior efficiency over Swank IL200 and Bentley Polyfilter.
    • Pall Ultipor showed comparable blood flow resistance and cellular integrity preservation to the Baxter filter.
    • Filter performance was consistent, with minor variations noted for 3-week-old blood.

    Conclusions:

    • The Pall Ultipor microfilter is a highly efficient option for preventing microemboli during blood transfusions.
    • It offers a favorable balance between filtration efficacy and preservation of blood product quality.
    • This microfilter represents a significant advancement in transfusion safety technology.

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