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Early puberty in adopted children.

D Mul1, W Oostdijk, S L S Drop

  • 1Erasmus University Medical Centre/Sophia Children's Hospital (Subdivision Endocrinology), Rotterdam, The Netherlands. Mul@alkg.azr.nl

Hormone Research
|May 15, 2002
PubMed
Summary

Early puberty in adopted children can lead to reduced final height. European studies explored treating this with Gonadotropin-releasing hormone (GnRH) agonist, examining auxological and psychological effects.

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Area of Science:

  • Pediatric Endocrinology
  • Adolescent Medicine
  • Child Psychology

Background:

  • Early puberty is common in adopted children.
  • Early puberty is linked to decreased final adult height.
  • GnRH agonist treatment is used in Europe for early puberty in adopted children.

Purpose of the Study:

  • To review current understanding of early puberty in adopted children.
  • To discuss prevalence, background, and treatment options.
  • To address auxological and psychological aspects.

Main Methods:

  • Review of European studies on GnRH agonist treatment for early puberty in adopted children.
  • Description of auxological data.
  • Inclusion of psychological assessments and reported studies.

Main Results:

  • Early puberty in adopted children is a recognized phenomenon.
  • GnRH agonist treatment has been studied in European cohorts.
  • Psychological effects are also considered alongside growth parameters.

Conclusions:

  • Further research is needed on the mechanisms of early puberty in adopted children.
  • Evaluation of final height outcomes from growth studies is essential.
  • Quality of life assessments are important for this population.

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