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Annular elastolytic giant cell granuloma.

Mark D Herron1, Cheryl M Coffin, Sheryll L Vanderhooft

  • 1Department of Dermatology, University of Utah School of Medicine, 30 North 1900 East, 4B454 School of Medicine, Salt Lake City, UT 84132, USA.

Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
|May 15, 2002
PubMed
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Annular elastolytic giant cell granuloma typically affects adults but can occur in children. This report details two pediatric cases of this rare skin condition.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Annular elastolytic giant cell granuloma (AEG) is a rare granulomatous skin condition.
  • AEG typically presents as annular papules and plaques on sun-exposed skin, primarily affecting adults in their fourth and fifth decades.
  • Literature review indicates a strong preponderance of AEG cases in adult populations.

Observation:

  • This study reports two unique cases of AEG occurring in children under 11 years of age.
  • The pediatric cases presented with characteristic annular lesions on sun-exposed areas.
  • Clinical and histopathological findings were consistent with AEG.

Findings:

  • The occurrence of AEG in prepubertal children is exceptionally rare.
  • These cases expand the known age spectrum for AEG presentation.

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  • The findings highlight that AEG should be considered in the differential diagnosis of granulomatous skin lesions in children.

    • Implications:

    • This study underscores the importance of considering rare dermatological conditions in pediatric patients.
    • The findings suggest that sun exposure may play a role in AEG development across different age groups.
    • Further research is warranted to understand the specific etiology and potential triggers of AEG in children.