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Randomized clinical trials of combined estrogen-androgen preparations: effects on sexual functioning
1Departments of Psychology and Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada. bsherwin@ego.psych.mcgill.ca
Objective:
To review the randomized controlled trials of the efficacy of combined estrogen-androgen (E-A) preparations on sexual functioning in postmenopausal women.
Patient(S):
Naturally and surgically menopausal women.
Main Outcome Measure(S):
Changes in aspects of sexual functioning.
Result(S):
In general, a high degree of agreement exists among the findings of these well-controlled trials that combined E-A preparations enhance psychological well-being as well as sexual desire and interest and, sometimes, increases the frequency of sexual intercourse and orgasm compared with estrogen-alone treatment in both naturally and surgically postmenopausal women.
Conclusion(S):
In selected cases, combined E-A therapy can enhance the quality of life for both naturally and surgically postmenopausal women.