Malaysian children with spina bifida: relationship between functional outcome and level of lesion

L C Ong1, Y N Lim, A Sofiah

  • 1Department of Paediatrics, Universiti Kebangsaan Malaysia, Kuala Lumpur. onglc@mail.hukm.ukm.my

Insights

The level of spinal lesions in children with spina bifida correlates with mobility issues. However, predicting continence and school placement based on lesion level is challenging for long-term care planning.

Area of Science:

  • Pediatric Neurology
  • Developmental Pediatrics
  • Rehabilitation Medicine

Background:

  • Spina bifida is a complex congenital condition affecting neural development.
  • Understanding the impact of lesion level is crucial for predicting functional outcomes in affected children.

Purpose of the Study:

  • To investigate the relationship between the spinal lesion level and various functional outcomes in children diagnosed with spina bifida.
  • To assess how different lesion levels correlate with mobility, continence, and educational placement.

Main Methods:

  • A prospective observational study involved 66 children with spina bifida attending a specialized clinic.
  • Data collection included serial physical examinations and parent interviews to assess mobility, neurosensory deficits, continence, and school placement.

Main Results:

  • Children with high-level lesions (thoracic/thoracolumbar) exhibited significantly more mobility challenges compared to those with intermediate (low lumbar) or low-level (sacral) lesions (p<0.001).
  • While diaper use varied by lesion level (p=0.005), no significant differences in soiling or urinary incontinence were observed across groups.
  • School placement, skin breakdown, epilepsy, and visual defects did not show significant differences based on lesion level.

Conclusions:

  • The level of spinal lesion strongly correlates with mobility outcomes in children with spina bifida.
  • Predicting functional outcomes such as continence and school placement based solely on lesion level is less reliable.
  • These findings are vital for providing realistic counseling to families and planning long-term rehabilitation strategies.
Abstract