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Detrusor myotomy: a 5-year review in unstable and non-compliant bladders
J M Potter1, P G Duffy, E M Gordon
1Department of Urology, Battle Hospital, Reading, UK.
Insights
Detrusor myotomy shows best outcomes for children with severe urinary incontinence and unstable detrusor contractions. Urodynamic factors like high detrusor leak-point pressure predict success.
Area of Science:
- Pediatric Urology
- Urodynamics
- Surgical Outcomes
Background:
- Urinary incontinence in children often requires surgical intervention.
- Detrusor myotomy is a surgical option for severe cases.
- Predicting surgical success is crucial for patient management.
Purpose of the Study:
- To identify urodynamic predictors of clinical success following detrusor myotomy in pediatric patients with urinary incontinence.
- To evaluate the long-term efficacy of detrusor myotomy.
Main Methods:
- A cohort of nine children (5-14 years) with severe urinary incontinence underwent detrusor myotomy.
- Pre-operative urodynamic assessments included bladder compliance and detrusor leak-point pressure.
- Patients were followed for a minimum of 5 years for clinical outcomes.
Main Results:
- Two patient subgroups emerged: normal compliance with unstable contractions (3 patients) and low compliance with few contractions (6 patients).
- Five patients had detrusor leak-point pressures > 40 cmH2O; four had < 40 cmH2O.
- Only two patients (both with unstable contractions and high leak-point pressure) achieved successful 5-year outcomes; seven remained incontinent.
Conclusions:
- Detrusor myotomy is most effective in children with marked phasic unstable detrusor contractions and a competent urethral sphincter.
- High detrusor leak-point pressure (> 40 cmH2O) may indicate a favorable outcome.
- This procedure may offer advantages in select patient populations compared to other treatments.
Objective:
To identify urodynamic factors that might determine the clinical outcome of detrusor myotomy in incontinent children.
Patients And Methods:
Six girls and three boys (aged 5-14 years) underwent detrusor myotomy for severe urinary incontinence. Seven children had spina bifida, one had traumatic paraplegia and one had low bladder compliance. The patients were followed for a minimum of 5 years.
Results:
Urodynamic studies before surgery showed that three patients had normal compliance with grossly unstable detrusor contractions, and six had low bladder compliance with few phasic detrusor contractions. Detrusor leak-point pressures were > 40 cmH2O in five patients and < 40 cmH2O in four. Only two patients, both with grossly unstable detrusor contractions and leak-point pressures of > 40 cmH2O, had a successful 5-year outcome. The other seven patients remained incontinent; six underwent further surgery and one died from unrelated causes.
Conclusion:
Detrusor myotomy appears to have the best outcome in those patients with marked phasic unstable detrusor contractions with a competent urethral sphincter. In this group it may have distinct advantages over more commonly used procedures.
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