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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
[Children and tuberculosis--diagnosis, treatment and follow-up]
1Barnesenteret Sentralsykehuset i Vestfold 3116 Tønsberg. mhand@online.no
Insights
Tuberculosis (TB) is rising in Norwegian children due to immigration. New clinical guidelines aim to improve early diagnosis and treatment, reducing childhood TB morbidity and mortality.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Context:
- Global rise in tuberculosis (TB) incidence since the 1980s.
- Increasing TB cases in the Norwegian child population, primarily linked to immigration.
- Need for updated clinical management strategies for pediatric TB in Norway.
Purpose:
- To develop evidence-based recommendations for the clinical management of tuberculosis in children in Norway.
- To provide guidance on diagnostic procedures, chemoprophylaxis, and treatment of latent and active TB disease.
- To emphasize the importance of collaboration between hospital pediatricians and primary healthcare services for effective follow-up.
Summary:
- Presents epidemiological data and clinical characteristics of pediatric TB in Norway.
- Outlines recommendations for diagnosis, prophylaxis, and treatment based on international and national guidelines.
- Highlights the critical role of local health services and interdisciplinary cooperation in managing childhood TB.
Impact:
- Aims to reduce mortality and morbidity associated with tuberculosis in children.
- Clinical guidelines are expected to improve the management of pediatric TB cases.
- Facilitates early detection and adequate treatment, enhancing patient outcomes and public health surveillance.
Background:
Since the 1980s, there has been an increase in the incidence of tuberculosis (TB) world-wide. Mainly due to immigration, the number of new TB cases in the Norwegian child population is also increasing. In March 2000, a selected group of Norwegian paediatricians interested in infectious diseases held a meeting to discuss the clinical management of tuberculosis in children, and develop recommendations.
Material And Methods:
The recommendations are based on current British, European and American recommendations. Two recent Norwegian recommendations on the management of tuberculosis in the general population were also reviewed.
Results:
Epidemiological data from Norway and the clinical characteristics of tuberculosis in children are briefly presented, followed by recommendations regarding diagnostic procedures, chemoprophylaxis, treatment of latent tuberculosis and disease. Local health services play a crucial role in the follow-up of children with tuberculosis, and the importance of co-operation between the hospital paediatrician and the primary health care service is emphasised.
Interpretation:
Early diagnosis and adequate treatment of tuberculosis is necessary to reduce mortality and morbidity from tuberculosis. Clinical guidelines may aid in management.
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