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Updated: Aug 10, 2026

Isolation of Brain-infiltrating Leukocytes
Published on: June 13, 2011
Psychological aspects of isolator therapy in acute leukaemia
Abstract:
Treatment under conditions of gnotobiotic isolation can augment the stress of adaptation to a diagnosis of leukaemia. Identification of the psychological problems experienced in isolator treatment can contribute to the effective maintenance of therapy. Individual patterns of adjustment to treatment relate to the psychological defence mechanisms employed to contend with the dependent position enforced by isolation. Psychiatric assessment can assist both patients and nursing staff with the management of their separate difficulties in this unfamiliar treatment situation. Psychological features of isolator treatment in ten patients with acute leukemia are described and suggestions proposed for psychological management of patients under isolator conditions.
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