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Pulmonary shunting during anaesthesia in man
Canadian Anaesthetists' Society Journal
|November 1, 1975
Summary
This study found that anesthesia and surgery can be performed without significantly increasing pulmonary shunting (Qs/Qt) in most patients. However, age was directly correlated with increased shunting.
Area of Science:
- Anesthesiology
- Cardiopulmonary Physiology
- Surgical Research
Background:
- Pulmonary shunting (Qs/Qt) can increase during anesthesia and surgery.
- Assessing Qs/Qt is crucial for patients undergoing surgical procedures.
- Controlled respiration is standard during many operations.
Purpose of the Study:
- To determine the effects of halothane and oxygen anesthesia on Qs/Qt in patients without pulmonary dysfunction.
- To evaluate if anesthesia and surgery significantly increase pulmonary shunting.
- To investigate the correlation between patient age and Qs/Qt.
Main Methods:
- Qs/Qt was measured in 22 patients undergoing surgery with controlled respiration under halothane and oxygen anesthesia.
- Patients were selected based on the absence of pre-existing pulmonary dysfunction.
- Statistical analysis was used to assess correlations and changes over time.
Main Results:
- 15 out of 22 patients exhibited minimal Qs/Qt (mean 3.9 ± 0.3%), suggesting anesthesia and surgery were well-tolerated.
- Seven patients showed increased Qs/Qt.
- Qs/Qt remained stable over time in both groups.
- A significant positive correlation was found between age and Qs/Qt (r=0.57, P<0.01).
Conclusions:
- Anesthesia and surgery can be performed in patients without pulmonary dysfunction with minimal increase in pulmonary shunting.
- Patient age is a significant factor influencing the level of pulmonary shunting during anesthesia and surgery.
- Further research may be warranted to explore age-related pulmonary changes during surgical procedures.