Tuberculosis in patients with myelodysplastic syndromes
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Published on: October 3, 2018
Hyo-Cheol Kim1, Jin Mo Goo, Hyun Beom Kim
1Department of Radiology, Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Korea.
Aim:
The purpose of our study was to describe radiological manifestations of tuberculosis in patients with myelodysplastic syndromes.
Materials And Methods:
Chest radiographs and CTs of 12 patients with tuberculosis among 195 consecutive patients with myelodysplastic syndrome, proved by bone marrow biopsy, were reviewed. Six of the 12 patients presented with tuberculosis and were subsequently found to have myelodysplastic syndrome.
Results:
Chest radiographs and CTs revealed pulmonary tuberculosis in all 12 patients and extrapulmonary tuberculous involvement in six (50%). Initial chest radiographic findings of pulmonary tuberculosis included a primary pattern (n = 6), a post-primary pattern (n = 3), a miliary pattern (n = 1), atypical infiltrates (n = 1) and normal radiograph (n = 1). Tuberculosis involved extrathoracic lymph nodes (n = 5), liver (n = 2), spleen (n = 2), kidney (n = 2), bowel (n = 2), pericardium (n = 2) peritoneum (n = 1) and rib (n = 1).
Conclusion:
Tuberculosis is a relatively common cause of infection in patients with myelodysplastic syndromes. The radiological appearance of pulmonary tuberculosis in myelodysplastic syndromes is often a primary pattern, and there is frequently extrapulmonary involvement.
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