Heart failure accompanied by sick euthyroid syndrome and exercise training
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D Psirropoulos1, N Lefkos, G Boudonas
1Coronary Unit of 2nd Department of Internal Medicine, Aristotelian University of Thessaloniki, Hippokration Hospital of Thessaloniki, Thessaloniki, Greece. dpsyro@hellasnet.gr
Abstract:
Sick euthyroid syndrome is defined as the decrease of serum free triiodothyronine with normal free L-thyroxin and thyrotropin. Its appearance in patients with chronic heart failure is an indicator of severity. Exercise training through a wide variety of mechanisms reverses sick euthyroid syndrome (normalization of free triiodothyronine levels) and improves the ability to exercise. There is a connection during exercise among dyspnea, hyperventilation, fatigue, catecholamines, a decrease in the number and function of beta-blocker receptors, and elevation of serum free triiodothyronine. It is not known whether sick euthyroid syndrome contributes to the development of heart failure or is only an attendant syndrome.
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