Related Experiment Video
Updated: Jul 15, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
[Fibrinolytic treatment. First results during the early postoperative period]
Insights
Fibrinolytic treatment with streptokinase successfully dissolved thrombi in Blalock-Taussig anastomoses in children with Fallot
Area of Science:
- Cardiology
- Pediatric Surgery
- Hematology
Background:
- Palliative shunt procedures for Fallot's disease can lead to thrombosis, particularly in pediatric patients.
- Early postoperative fibrinolytic treatment carries a risk of hemorrhage.
Observation:
- Five children with Fallot's disease experienced thrombosis of their Blalock-Taussig anastomoses.
- These anastomoses are crucial for maintaining blood flow in palliative cardiac surgery.
Findings:
- Successful thrombolysis was achieved using streptokinase in all five pediatric cases.
- This intervention improved the children's clinical condition.
Implications:
- Fibrinolytic therapy should be considered for early thrombosis after anastomosing operations in pediatric cardiac surgery.
- This treatment may help defer the need for further surgical interventions.
Abstract:
Fibrinolytic treatment during the early post-operative period is associated with a real danger of hemorrhage. On the other hand, in palliative shunt procedures in Fallot's disease, especially in small children, the anastomoses may thrombose. In such cases the therapeutic lysis of the thrombus improves the child's condition and may defer further surgery. The authors describe five cases of children with Fallot's disease and thrombosis of Blalock-Taussig anastomoses who were successfully treated by streptokinase. They conclude that fibrinolytic treatment should be considered in early thrombosis following anastomosing operations.
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Clot Retraction and Fibrinolysis
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Assessment:
1. Clinical Evaluation:
History:
Venous Thrombosis III: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

