Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mouse Models of Cancer Study

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sensitivity of a model oscillator to shifts in the voltage-dependence of one or more ionic currents.

Journal of neurophysiology·2026

Same author

Blue plaque review series: Thomas Graham Brown: Before his time.

Experimental physiology·2026

Same author

Quantitative Neuropeptidomics Reveals Thermal Acclimation-Induced Remodeling of Peptidergic Signaling in the American Lobster <i>Homarus americanus</i>.

bioRxiv : the preprint server for biology·2026

Same author

Temperature and pH-dependent potassium currents of muscles of the stomatogastric nervous system of the crab, <i>Cancer borealis</i>.

iScience·2026

Same author

Persistent adaptation through dual-timescale regulation of ion channel properties.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

The combined effects of temperature and salinity on the stomatogastric nervous system of two species of decapod crustacea.

Journal of neurophysiology·2026

Same journal

Daily briefing: 'Cyborg' cockroaches breathe underwater with printed suit.

Nature·2026

Same journal

China boosts prestigious grants for young scientists - will it ease competition?

Nature·2026

Same journal

Incoming US science academy chief vows to 'double down' on research.

Nature·2026

Same journal

Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization.

Nature·2026

Same journal

Electrodeposited self-assembled molecules for perovskite photovoltaics.

Nature·2026

Same journal

Neutrino's nursery found: the 'Shadow Blaster'.

Nature·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 19, 2026

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach

Published on: June 11, 2017

Non-mammalian models for studying neural development and function.

¹Volen Center, Brandeis University, Waltham, MA 02454-9110, USA. marder@brandeis.edu

|May 17, 2002

Summary

This summary is machine-generated.

Non-mammalian nervous systems offer unique advantages for neuroscience research. Studying these systems reveals fundamental principles applicable across all nervous systems.

More Related Videos

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification

Published on: March 24, 2023

Fabrication of an Expandable Brain Matrix Customizable Across Developmental Stages

Fabrication of an Expandable Brain Matrix Customizable Across Developmental Stages

Published on: February 20, 2026

Related Experiment Videos

Last Updated: Jun 19, 2026

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach

Published on: June 11, 2017

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification

Author Spotlight: Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification

Published on: March 24, 2023

Fabrication of an Expandable Brain Matrix Customizable Across Developmental Stages

Fabrication of an Expandable Brain Matrix Customizable Across Developmental Stages

Published on: February 20, 2026

Area of Science:

Neuroscience
Comparative Biology

Background:

Historically, researchers selected specific animal models to investigate neurological questions.
Non-mammalian nervous systems remain valuable tools in contemporary neuroscience.

Purpose of the Study:

To highlight the utility of non-mammalian models in neuroscience.
To demonstrate how unique adaptations in these models can elucidate general neural principles.

Main Methods:

Review of historical and current neuroscience research utilizing non-mammalian preparations.
Analysis of how specific ecological niches and body plans inform experimental design.

Main Results:

Non-mammalian nervous systems provide accessible and informative models for complex neuroscience problems.
Investigating unique adaptations reveals broadly applicable principles of nervous system function.

Conclusions:

The study of non-mammalian nervous systems continues to be crucial for advancing fundamental neuroscience.
Comparative approaches using diverse animal models yield generalizable insights into neural mechanisms.