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Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
Published on: June 6, 2017
Cyclin G: a regulator of the p53-Mdm2 network
1Department of Cell Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Developmental Cell
|May 23, 2002
Abstract:
A recent study published in the April issue of Molecular Cell has shown that cyclin G, a p53 target, is a regulatory component of the active PP2A holoenzyme, which activates Mdm2 through dephosphorylation. These findings suggest that cyclin G is a key regulator of the p53-Mdm2 network.
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