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CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences
Loïc Ponger1, Dominique Mouchiroud
1Laboratoire de Biométrie et Biologie Evolutive, UMR CNRS 5558 - UniversitéClaude Bernard, 43, Bd du 11 Novembre 1918, 69622 Villeurbanne Cedex, France. ponger@biomserv.univ-lyon1.fr
Results:
CpGProD is an application for identifying mammalian promoter regions associated with CpG islands in large genomic sequences. Although it is strictly dedicated to this particular promoter class corresponding to approximately 50% of the genes, CpGProD exhibits a higher sensitivity and specificity than other tools used for promoter prediction. Notably, CpGProD uses different parameters according to species (human, mouse) studied. Moreover, CpGProD predicts the promoter orientation on the DNA strand.
Availability:
http://pbil.univ-lyon1.fr/software/cpgprod.html
Supplementary Information:
http://pbil.univ-lyon1.fr/software/cpgprod.html