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Updated: Aug 8, 2026
04:44
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
The chest radiograph in ankylosing spondylitis
Clinical Radiology
|October 1, 1975
Summary
Ankylosing spondylitis patients show higher rates of upper lobe fibrosis and pulmonary abnormalities. These lung issues are linked to severe spinal ankylosis, not blood markers.
Area of Science:
- Rheumatology
- Pulmonology
- Radiology
Background:
- Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the spine.
- Pulmonary complications in AS are recognized but require further characterization.
Observation:
- A study investigated pulmonary abnormalities in 42 ankylosing spondylitis patients.
- Upper lobe fibrosis was observed in 14.3% of patients.
Findings:
- Patients with upper lobe fibrosis exhibited total spinal ankylosis and peripheral joint involvement.
- 30.9% of AS patients had other focal pulmonary abnormalities, significantly more than controls.
- No correlation was found between radiological disease extent and hematological/biochemical markers.
- Radiotherapy was not identified as a cause for these pulmonary changes.
Implications:
- Pulmonary involvement, particularly upper lobe fibrosis, is a significant concern in ankylosing spondylitis.
- These findings highlight the need for respiratory monitoring in AS patients.
- Further research is warranted to understand the pathogenesis and management of pulmonary complications in AS.
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