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Occupational risk for hepatitis A and hepatitis E among health care professionals?
M Nübling1, F Hofmann, F W Tiller
1Dept of Applied Physiology, Occupational Medicine and Infectiology, University of Wuppertal, Germany. ffas.freiburg@t-online.de
Background:
Since transmission routes of hepatitis E virus (HEV) and hepatitis A virus (HAV) are believed to be similar, comparable risk factors and a correlation between the two seroprevalence rates may be assumed.
Materials And Methods:
Anti-HAV and anti-HEV serology was assessed in 511 German subjects from nursing, pediatric nursing and administration groups, none of whom had been vaccinated against HAV. At the same time a standardized questionnaire on occupational and individual parameters was completed.
Results:
Overall seroprevalence for anti-HEV was 3.9%, for anti-HAV 28%. Multivariate analysis revealed that anti-HEV seroprevalence was significantLy higher in persons working in emergency admission or in surgery, while persons working in children's psychiatry were more likely to be anti-HAV positive. Comparing the two serological resulLts, no contingency difference was found (chi2 = 0.42 (df = 1), p > 0.05).
Conclusion:
Specific departments of health care show higher prevalence of anti-HAV or anti-HEV. In the case of HEV further studies in the exposed working field are needed. Since no connection between the two serological results was found, transmission mechanisms might be (partly) different.
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