Related Experiment Videos
Comparative study of permanganate oxidation reactions of nucleotide bases by spectroscopy
Chinh T Bui1, Richard G H Cotton
1Genomic Disorders Research Centre, University of Melbourne, 7th Floor, Daly Wing, 41 Victoria Parade, Fitzroy, Melbourne, Victoria 3065, Australia. chinhbui@mail.medstv.unimelb.edu.au
Bioorganic Chemistry
|May 22, 2002
Abstract:
The permanganate oxidation of free nucleotide bases was successfully studied in aqueous solution of tetraethylammonium chloride using spectroscopic techniques. The reaction was highly selective toward thymine and uracil, less with cytosine, very little reaction on guanine, and no reaction on adenine.