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[Effect of Gastrodia on rotation induced motion sickness in mice]
1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Objective:
To observe the effect of Gastrodia on motion sickness induced by rotation in mice.
Method:
Clockwise and anticlockwise accelerated rotations up to 180 degrees/s for 10 min were used to induce symptoms of motion sickness such as condition taste aversion (CTA), decrease of spontaneous locomotion and impaired ability of space identification in water-maze.
Result:
Gastrodia could improve the response of CTA, increase spontaneous locomotion, and enhance the ability of learning and memory in water-maze in mice after the rotation.
Conclusion:
Symptoms of motion sickness induced by rotation could be improved by Gastrodia treatment.