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Potential for immune reconstitution through G-CSF treatment of HIV patients
Sonja Von Aulock1, Thomas Hartung
1Biochemical Pharmacology, University of Konstanz, Germany.
Archivum Immunologiae Et Therapiae Experimentalis
|May 23, 2002
Abstract:
New treatment strategies for HIV/AIDS are very successful in reducing viral load. However, reconstitution of the immune system takes about one year and may be insufficient or remain incomplete. During this time the patient remains prone to opportunistic infections as a result of the complex immune dysfunction caused by the virus. Recombinant granulocyte colony-stimulating factor (G-CSF) has diverse immunomodulatory properties which may be beneficial in aiding immune reconstitution.