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Akaloid screening. VII.

S J Smolenski, H Silinis, N R Farnsworth

    Lloydia
    |September 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    This study screened 1,005 plant extracts for alkaloids, finding 190 positive results. A significant 153 species contained novel alkaloids, expanding the known alkaloid-bearing plant database.

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    Area of Science:

    • Phytochemistry
    • Natural Products Chemistry
    • Pharmacognosy

    Background:

    • Alkaloids are a diverse class of naturally occurring organic compounds that contain at least one nitrogen atom.
    • Plant-derived alkaloids have significant pharmacological activities and are crucial in drug discovery.
    • Previous research has identified alkaloids in numerous plant species, but many remain unexplored.

    Purpose of the Study:

    • To screen a collection of plant extracts for the presence of alkaloids.
    • To identify plant species containing alkaloids that are new to the scientific literature.
    • To contribute to the growing knowledge base of plant-derived alkaloids.

    Main Methods:

    • Screening of 1,005 plant extracts using established chemical tests for alkaloids.

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  • Identification and documentation of plant species yielding positive alkaloid tests.
  • Comparison with existing literature to determine novelty of findings.

    • Main Results:

    • 190 out of 1,005 plant extracts (18.91%) tested positive for alkaloids.
    • 153 plant species containing alkaloids were identified as new discoveries.
    • This adds to the cumulative findings from 5,995 previously screened extracts, representing 4,888 species, with 1,336 positive alkaloid tests.

    Conclusions:

    • The screening effort successfully identified a substantial number of plant species containing alkaloids.
    • The discovery of 153 new alkaloid-bearing species highlights the untapped potential of plant biodiversity for novel compound discovery.
    • Continued phytochemical screening is essential for uncovering new natural products with potential therapeutic applications.