Short-term regulation of PDE4 activity

Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.

Oral diseases·2014

Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP.

The Biochemical journal·2000

Evidence for the presence of several phosphodiesterase isoforms in brown adipose tissue of Zucker rats: modulation of PDE2 by the fa gene expression.

FEBS letters·1999

Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A.

The Biochemical journal·1999

Mechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes.

The Biochemical journal·1999

Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I.

Biochemical and biophysical research communications·1998

NMDA receptor subunit-dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons.

British journal of pharmacology·2026

Development of glutamatergic antipsychotics requires efficient synaptic glutamatergic transmission while preventing NMDA receptor down-regulation and overactivation of extrasynaptic transmission.

British journal of pharmacology·2026

Up-regulation of the kinase LRRK2, in enteric glia contributes to mucosal barrier impairment in Parkinson's disease via secretory autophagy.

British journal of pharmacology·2026

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation.

British journal of pharmacology·2026

Therapeutic potential of tanshinones in ischaemia-reperfusion injury: Bioactive analogues, pharmacology and mechanisms.

British journal of pharmacology·2026

Long non-coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets.

British journal of pharmacology·2026

Thin-Layer Electrochemistry: Visualizing the Diffusion Layer During Chronoamperometry and Cyclic Voltammetry.

Journal of chemical education·2026

New perspective on acute boutonniere deformity: An anatomical study with illustrative case report.

Journal of hand and microsurgery·2026

Prediction of second-order rate constants for reactions between contaminants and reactive species by a ChemBERTa-based QSAR model.

Journal of environmental management·2026

Unexpected Radiation Chemistry of Borate Buffer. II: Second-Order Decay.

The journal of physical chemistry. B·2026

The Effect of Hydrogen Sulfide and Reactive Sulfur Species on Bacterial Virulence and Antibiotic Sensitivity.

International journal of molecular sciences·2026

Competing Photoisomerization and Excited-State Intramolecular Proton Transfer in a Visible-Light-Driven Salicylidene Schiff Base Functionalized Molecular Motor: Insights from Ultrafast Nonadiabatic Dynamics Simulations.

International journal of molecular sciences·2026

Related Experiment Videos

Short-term regulation of PDE4 activity

Related Concept Videos

Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.

Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP.

Evidence for the presence of several phosphodiesterase isoforms in brown adipose tissue of Zucker rats: modulation of PDE2 by the fa gene expression.

Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A.

Mechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes.

Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I.

NMDA receptor subunit-dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons.

Development of glutamatergic antipsychotics requires efficient synaptic glutamatergic transmission while preventing NMDA receptor down-regulation and overactivation of extrasynaptic transmission.

Up-regulation of the kinase LRRK2, in enteric glia contributes to mucosal barrier impairment in Parkinson's disease via secretory autophagy.

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation.

Therapeutic potential of tanshinones in ischaemia-reperfusion injury: Bioactive analogues, pharmacology and mechanisms.

Long non-coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets.

Thin-Layer Electrochemistry: Visualizing the Diffusion Layer During Chronoamperometry and Cyclic Voltammetry.

New perspective on acute boutonniere deformity: An anatomical study with illustrative case report.

Prediction of second-order rate constants for reactions between contaminants and reactive species by a ChemBERTa-based QSAR model.

Unexpected Radiation Chemistry of Borate Buffer. II: Second-Order Decay.

The Effect of Hydrogen Sulfide and Reactive Sulfur Species on Bacterial Virulence and Antibiotic Sensitivity.

Competing Photoisomerization and Excited-State Intramolecular Proton Transfer in a Visible-Light-Driven Salicylidene Schiff Base Functionalized Molecular Motor: Insights from Ultrafast Nonadiabatic Dynamics Simulations.

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Short-term regulation of PDE4 activity

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