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The incidence of guiac positive stools in newborns and infants
1Children's Hospital of Wisconsin, Wauwatosa, WI, USA.
Insights
Fecal occult blood was detected in 22.8% of hospitalized infants without gastrointestinal issues. This finding suggests causes beyond milk-related sensitivities for positive occult blood tests in infants.
Area of Science:
- Pediatric Medicine
- Gastroenterology
- Clinical Diagnostics
Background:
- Occult blood in stool can indicate gastrointestinal bleeding.
- Identifying the cause is crucial for appropriate infant care.
- Hospitalized infants may present with non-gastrointestinal medical problems.
Purpose of the Study:
- To determine the incidence of fecal occult blood in hospitalized infants.
- To investigate infants with medical issues unrelated to the gastrointestinal tract.
Main Methods:
- Study included 180 infants aged 2 days to 1 year.
- Stool samples were collected during hospitalization.
- Propper Seracult test was used for in vitro diagnostic evaluation of fecal occult blood.
Main Results:
- 77.2% of infants had negative results for fecal occult blood (guaiac negative).
- 22.8% of infants showed positive results for fecal occult blood (guaiac positive) during their hospital stay.
Conclusions:
- Positive fecal occult blood tests in most infants were not linked to milk-based formulas or breast milk.
- Findings suggest non-allergic, non-milk-induced enterocolitis as potential causes.
- Further investigation is needed to determine the etiology of occult blood in this population.
Purpose:
To describe the frequency of occult blood in the stool of newborns and infants who were hospitalized for a medical problem other than a gastrointestinal disorder.
Method:
One hundred and eighty patients, ages 2 days to 1 year of age, participated in the study. Stool was collected and assayed for fecal occult blood using the Propper Seracult test for invitro diagnostic evaluation.
Findings:
The majority of infants, 77.2%, had guiac negative stools for the entire hospitalization, while 22.8% had guiac positive stools during part or all of the hospitalization.
Conclusions:
Since most of the infants who tested guiac positive were not receiving a milk-based formula or breastmilk, it would suggest a cause other than allergic sensitivity or milk-induced enterocolitis.
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