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Synthesis of new pyrroles and their biological activities
V P Chavan1, A S Mane, S B Bhawsar
1Department of Chemistry, Dr. B. A. Marathwada University, Aurangabad 431 004, India.
Hindustan Antibiotics Bulletin
|May 25, 2002
Abstract:
Coumarino acid hydrazides and acid hydrazide of 2-oxy 3, 5, 6-trichloropyridine were prepared in two steps. These acid hydrazides on condensation with Acetonyl acetone i.e. 2,5-hexanedione yields new pyrroles. These pyrroles showed good to moderate antimicrobial activities against Alternaria brassicicola, Aspergillus niger, E. coli and Lactobacillus.