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[Benefits of pyeloplasty in children with pyeloureteral stenosis: study of somatic development and differential renal
Y Royo Cuadra1, J Maldonado Artero, J Spuch Sánchez
1Servicio de Cirugía Pediátrica, Hospital Universitario Juan XXIII, C/Dr. Mallafré Guasch, 43005 Tarragona.
Insights
Pyeloplasty effectively treats ureteropelvic junction obstruction, significantly improving differential renal function and promoting healthy body growth in pediatric patients. This surgical option is recommended for selected symptomatic and asymptomatic cases with impaired kidney function.
Area of Science:
- Pediatric Urology
- Surgical Oncology
- Nephrology
Context:
- Ureteropelvic junction (UPJ) obstruction is a common cause of hydronephrosis in children.
- Management controversies exist regarding the optimal treatment strategy for UPJ obstruction.
- Pyeloplasty is a primary surgical intervention for UPJ obstruction.
Purpose:
- To evaluate the indications for pyeloplasty in pediatric UPJ obstruction.
- To assess the functional outcomes of pyeloplasty using differential renal function (DRF) and diuretic renography.
- To determine the impact of pyeloplasty on somatic growth in children.
Summary:
- This study reviewed 16 patients (17 kidneys) who underwent pyeloplasty for UPJ obstruction between 1995-1999.
- Indications included symptomatic cases and asymptomatic cases with abnormal renographic curves or DRF.
- Postoperative assessment showed significant improvement in DRF and renographic drainage patterns, alongside enhanced body growth.
Impact:
- Pyeloplasty demonstrates effectiveness in treating UPJ obstruction, leading to improved differential renal function.
- The procedure positively influences body growth in pediatric patients with UPJ obstruction.
- This study supports pyeloplasty as a valuable therapeutic option for selected UPJ obstruction cases.
Introduction:
Under the actual controversy about the management of hydronephrosis for ureteropelvic junction obstruction, our objective has been to evaluate the indications and the effects of pyeloplasty as therapeutic option.
Material And Methods:
We have reviewed the charts of patients who underwent pyeloplasty, in special concerns at the preoperatory study and the postoperatory control by means of differential renal function (DRF) and half-time drainage (T1/2) on curves of Tc99m MAG3 diuretic renogram, and the effects in the body growth.
Results:
Between 1995-1999 a total of 16 patients (17 kidneys) underwent pyeloplasty (range: 2 months to 12 years), selecting for the surgical treatment the symptomatic cases and the asymptomatics with alteration of renographic curve and/or DRF. The left side was involved in 12 cases, the right side in 3, and one case was bilateral. The malformation was detected by prenatual ultrasonography on 56.25% of cases and by several symptoms (abdominal pain, infection) in remaIns. The preoperatory DRF was normal (> or = 45%) in 53.3% and deteriorated in 46.7%. Postoperatively, global differential renal function improved significantly, with normal values in 66.7% of kidneys at first control and 75% at the second one. All the cases presented before surgery an obstructed renographic curve, with a half-time superior to 20 minutes; after pyeloplasty the excretory pattern in the diuresis renogram improved significantly, with a normal pattern (T1/2 < 10') in 54%, indeterminate (T1/2 between 11 and 20') in 26.7% and obstructive (T1/2 > 20') in 20% of cases. At the age of surgery, 29.4% of children was below the 50th percentile in weight; postoperatively, only 5.9% was, demonstrating a significant increment in all the cases.
Conclusions:
Pyeloplasty is an effective technique for the treatment of ureteropelvic junction obstruction in the selected cases, demonstrating a significant of differential renal function and body growth.
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