Rapid eye movement sleep behavior disorder in children with autism
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Updated: Oct 1, 2026

Eye Tracking Young Children with Autism
Published on: March 27, 2012
Shanti S Thirumalai1, Richard A Shubin, Ricki Robinson
1Department of Neurology, Children's Hospital, Los Angeles, CA 90027, USA. sthirumalai@chla.usc.edu
Insights
Five children with autism were diagnosed with REM sleep behavior disorder, a condition usually seen in older men. This finding may change how we understand autism and its treatments.
Area of Science:
- Neurology
- Sleep Medicine
- Developmental Pediatrics
Background:
- Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition.
- Sleep disturbances, including nocturnal awakenings, are common in children with autism.
- Rapid Eye Movement (REM) sleep behavior disorder (RBD) is typically associated with neurodegenerative diseases in elderly males.
Observation:
- Nocturnal polysomnography was conducted on 11 children diagnosed with autism and exhibiting sleep disruption.
- The study aimed to investigate potential underlying sleep disorders contributing to symptoms in autistic children.
Findings:
- Rapid Eye Movement (REM) sleep behavior disorder (RBD) was identified in 5 out of the 11 autistic children studied.
- This represents a significant prevalence of RBD in this pediatric autism cohort.
- The presence of RBD in children with autism was unexpected given its typical demographic association.
Implications:
- The identification of RBD in autistic children suggests potential shared neurochemical or neurophysiologic pathways between autism and RBD.
- This finding could significantly advance the understanding of the underlying mechanisms of autism spectrum disorder.
- Accurate diagnosis of RBD in autistic children allows for targeted treatment with medications like clonazepam, improving sleep consolidation and daytime functioning.
Abstract:
We performed nocturnal polysomnography on 11 children with autism who had symptoms of disrupted sleep and nocturnal awakenings. We identified rapid eye movement (REM) sleep behavior disorder in 5 of these 11 patients. Since REM sleep behavior disorder typically affects elderly males with neurodegenerative diseases, the identification of this phenomenon in autistic children could have profound implications for our understanding of the neurochemical and neurophysiologic bases of autism. Further, accurate diagnosis of REM sleep behavior disorder would enable specific treatment with clonazepam and help the family and the child consolidate sleep and improve daytime performance.
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REM Sleep Behavior Disorder
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