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Related Experiment Videos

Topical testosterone therapy for penile growth.

S C Jacobs, G W Kaplan, R F Gittes

    Urology
    |December 1, 1975
    PubMed
    Summary

    Topical testosterone cream applied daily to the penis stimulated penile growth in three prepubertal males. This suggests testosterone

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    Area of Science:

    • Pediatric Endocrinology
    • Andrology
    • Dermatology

    Background:

    • Prepubertal males have limited options for penile growth stimulation.
    • Systemic effects of topical medications can influence growth and development.

    Purpose of the Study:

    • To investigate the efficacy of topical testosterone cream in promoting penile growth in prepubertal males.
    • To determine if penile growth is due to local application or systemic absorption.

    Main Methods:

    • Three prepubertal males received daily topical application of 5% testosterone cream to the penis.
    • Serum testosterone levels were monitored during the treatment period.

    Main Results:

    • All three patients exhibited significant penile growth.
    • Two patients showed a dramatic increase in serum testosterone levels.
    • No significant adverse effects were reported.

    Conclusions:

    • Topical testosterone application appears to be an effective method for inducing penile growth in prepubertal males.
    • Penile growth is likely mediated by systemic absorption and hormonal effects rather than solely local action.
    • Further research is warranted to confirm these findings and establish optimal treatment protocols.

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