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Updated: Oct 1, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
Published on: August 22, 2018
Diastereocontrolled synthesis of trans- and cis-meso-cyclopentene aziridines
Darren Caine1, Peter O'Brien, Clare M Rosser
1Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
Abstract:
[reaction: see text] The synthesis of novel substituted meso-aziridines is described: aziridination of 4-tert-butyldiphenylsilyloxy-cyclopent-1-ene is trans selective using Cu(I)/PhI=NSO(2)Ar and cis selective using PhNMe(3)(+)Br(3)(-)/Chloramine-T.
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