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Novel dipeptide macrocycles from 4-oxo, -thio, and -amino-substituted proline derivatives
Ashok Arasappan1, Kevin X Chen, F George Njoroge
1Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. ashok.arasappan@spcorp.com
The Journal of Organic Chemistry
|May 25, 2002
Abstract:
Dipeptide macrocycles of type A have been constructed in a versatile manner from the corresponding 4-heteroatom-substituted proline derivatives using an intramolecular Mitsunobu strategy.