Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A technique for sequential segmental neuromuscular stimulation with closed loop feedback control.

Erik D H Zonnevijlle1, Gustavo Perez Abadia, Naveen N Somia

  • 1Division of Plastic and Reconstructive Surgery, Department of Surgery, School of Medicine, University of Louisville, Kentucky, USA. zon@bart.nl

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
|May 25, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Are Treatment Adherence Factors Apparent in Patients with Asthma and to Physicians? Results from the APPaRENT 3 Survey.

Advances in therapy·2025
Same author

APPaRENT 3: Asthma Patients' and Physicians' Perspectives on the Burden and Management of Asthma in Seven Countries.

Advances in therapy·2024
Same author

The relation between clinically diagnosed and parent-reported feeding difficulties in children with and without clefts.

European journal of pediatrics·2023
Same author

Human adult, pediatric and microtia auricular cartilage harbor fibronectin-adhering progenitor cells with regenerative ear reconstruction potential.

iScience·2022
Same author

Baby Fe's first environmental footprint - There must be a better way!

International journal of surgery (London, England)·2022
Same author

Intensive hands-on microsurgery course provides a solid foundation for performing clinical microvascular surgery.

European journal of trauma and emergency surgery : official publication of the European Trauma Society·2022
Same journal

Associations between Age, Treatment Modality and Survival in Atypical Meningioma: Analysis of the SEER Database, 2000-2021.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026
Same journal

The Effect of Moxibustion at the Dazhui Point on Hypothermia and Maternal Comfort During Cesarean Delivery: A Randomized Controlled Trial.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026
Same journal

Risk Factors, Cancer Types and Prognostic Significance of Second Primary Cancer After Early-, Intermediate- and Late-Onset Colorectal Cancer: A Retrospective Study in a Chinese High-Volume Cancer Center.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026
Same journal

Intensive Care Unit Admissions Following Enhanced Recovery After Surgery for Laparoscopic Repair of Perforated Peptic Ulcer.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026
Same journal

Comparison of Transumbilical Single‑Port and Multi‑Port Laparoscopic Myomectomy in Patients with Uterine Fibroids: Effects on Stress Response, Immune Function, and Incision Cosmetic Outcomes.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026
Same journal

Correction.

Journal of investigative surgery : the official journal of the Academy of Surgical Research·2026
See all related articles

Closed-loop control optimizes sequential muscle stimulation in dynamic myoplasty, improving blood perfusion and reducing fatigue. This approach enhances myoplasty performance by regulating contractions based on real-time feedback.

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Surgical Innovation

Background:

  • Dynamic myoplasty uses donor skeletal muscle to assist or replace dysfunctional muscle.
  • Current methods like sequential stimulation improve perfusion but still lead to muscle fatigue.
  • Electrical stimulation is key for training and animating myoplasty, but current techniques have limitations.

Purpose of the Study:

  • To test the feasibility of closed-loop control for optimizing sequentially stimulated dynamic myoplasty.
  • To develop and evaluate a stimulation algorithm for improved myoplasty performance.
  • To compare amplitude and frequency modulation techniques for closed-loop control.

Main Methods:

  • A closed-loop control system was developed using a stimulation algorithm.

Related Experiment Videos

  • The system was tested on a canine gracilis muscle neo-sphincter.
  • Lumen pressure provided feedback to regulate stimulation via three control parameters.

    • Main Results:

    • Closed-loop feedback successfully maintained target pressures within a 10% deviation.
    • Optimized control parameters (4 Hz correction frequency, 4% threshold, 0.3 s transition time) were identified.
    • Amplitude modulation proved effective within the closed-loop system.

    Conclusions:

    • Closed-loop control is a feasible strategy to enhance sequentially stimulated myoplasty performance.
    • This system offers a potential blueprint for improving chronic myoplasty function.
    • Further development of small-scale systems is needed to explore long-term benefits.