[Histochemical study of choroid plexuses, ependymal epithelium and subcommissural organ in experimental conditions...

Activities of some dehydrogenases (DH) belonging to the metabolism of glucose, glutamic acid and gamma-aminobutyric acid, and to Kreb's cycle are investigated in choroid plexuses, ependymal epithelium and subcommissural organ of the rat. The observations are completed by detection of acid phosphatase activity. Metabolic modifications are demonstrated following carbonic anhydrase inhibition and plasmatic sodium hypertonicity. After treatment with Diamox, an increase of the activity of the various DH considered is observed in choroid plexuses. The effect seems to be only transient. Plasmatic hypertonicity induces some changes in DH activity in the different tissues. Acid phosphatase activity remains unchanged in these conditions.