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A hemodynamic approach to resistant hypertension
S J Taler1, J Augustine, S C Textor
1Department of Medicine, Division of Hypertension and Internal Medicine, Mayo Clinic, Rochester, MN 55905.
Congestive Heart Failure (Greenwich, Conn.)
|May 25, 2002
Summary
Resistant hypertension, despite affecting few patients, causes significant organ damage and cardiovascular risks. Thoracic bioimpedance measurements can guide effective combination drug therapy for this condition.
Area of Science:
- Cardiology
- Nephrology
- Clinical Pharmacology
Background:
- Resistant hypertension impacts a small subset of treated hypertensive individuals.
- This condition leads to disproportionately high rates of target organ damage.
- It significantly increases the risk of cardiovascular events.
Purpose of the Study:
- To describe the clinical features of resistant hypertension.
- To outline strategies for adjusting drug treatment in resistant hypertension.
- To evaluate the utility of thoracic bioimpedance in guiding antihypertensive therapy.
Main Methods:
- Case study of a resistant hypertensive patient.
- Serial hemodynamic measurements.
- Utilized thoracic bioimpedance technology.
Main Results:
- Clinical features of resistant hypertension were detailed.
- Treatment adjustments were explored.
- Thoracic bioimpedance provided data to inform combination therapy selection.
Conclusions:
- Serial hemodynamic monitoring via thoracic bioimpedance offers a rational approach.
- This method aids in selecting effective antihypertensive drug combinations.
- It can help manage complex cases of resistant hypertension.