Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aerosol delivery during mechanical ventilation.

D Hess1

  • 1Respiratory Care, Massachusetts General Hospital, Anaesthesia, Harvard Medical School, Boston, MA, USA. dhess@partners.org

Minerva Anestesiologica
|May 25, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A retrospective analysis of phase I and phase I/II investigator-initiated clinical trials conducted by the Swiss Group for Clinical Cancer Research (SAKK).

ESMO open·2025
Same author

Healthcare-associated infection impact with bioaerosol treatment and COVID-19 mitigation measures.

The Journal of hospital infection·2021
Same author

Nelfinavir and lenalidomide/dexamethasone in patients with lenalidomide-refractory multiple myeloma. A phase I/II Trial (SAKK 39/10).

Blood cancer journal·2019
Same author

Vacuum-assisted early transanal closure of leaking low colorectal anastomoses: the CLEAN study.

Surgical endoscopy·2017
Same author

Phase I trial of the oral smoothened inhibitor sonidegib in combination with paclitaxel in patients with advanced solid tumors.

Investigational new drugs·2017
Same author

Do all patients with advanced HER2 positive breast cancer need upfront-chemo when receiving trastuzumab? Randomized phase III trial SAKK 22/99.

Annals of oncology : official journal of the European Society for Medical Oncology·2016
Same journal

Rectus sheath block for analgesia in open abdominal surgery: a systematic review, meta-analysis and trial sequential analysis.

Minerva anestesiologica·2026
Same journal

Highlights from the June 2026 issue.

Minerva anestesiologica·2026
Same journal

Validation of the Gendolcat model for chronic postsurgical pain after cesarean section: a multicenter study.

Minerva anestesiologica·2026
Same journal

Dual block strategy for complex incision in pediatric kidney transplantation: M-TAPA and quadroiliac plane block combination.

Minerva anestesiologica·2026
Same journal

Technical note: a novel fully visualized, glottic-sparing strategy for infant one-lung ventilation.

Minerva anestesiologica·2026
Same journal

Ultrasound-guided recto-intercostal fascial plane block facilitating early extubation following pediatric subxiphoid pericardial window surgery.

Minerva anestesiologica·2026
See all related articles

Metered dose inhalers (MDIs) offer the most efficient aerosol delivery during mechanical ventilation. Nebulizers provide the largest absolute amount of drug delivery in these patients.

Area of Science:

  • Respiratory Medicine
  • Pharmacology

Background:

  • Mechanical ventilation requires effective aerosolized drug delivery.
  • Both nebulizers and metered dose inhalers (MDIs) are used for this purpose.

Purpose of the Study:

  • To compare the efficiency and absolute drug delivery of nebulizers versus MDIs during mechanical ventilation.

Main Methods:

  • Aerosol delivery methods were assessed during mechanical ventilation.

Main Results:

  • Metered dose inhalers (MDIs) demonstrated higher efficiency in aerosol delivery.
  • Nebulizers resulted in a greater absolute amount of drug delivered.

Conclusions:

  • The choice between nebulizers and MDIs depends on whether efficiency or absolute drug amount is prioritized.

Related Experiment Videos

  • Optimizing aerosol delivery is crucial for effective treatment in mechanically ventilated patients.