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Published on: May 30, 2020
Fludarabine-induced eosinophilia: case report
1Sérvice d'Hématologie, Institut Gustave-Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France. voutsadakis@igr.fr
Abstract:
Eosinophilia induced by nucleoside analogs has been described in a handful of case reports and during the treatment of both chronic lymphocytic leukemia (CLL) and follicular non-Hodgkin's lymphoma (NHL). This paper reports an additional case of fludarabine-induced eosinophilia during the treatment of CLL. The patient, a 58-year-old man, developed peripheral eosinophilia with a peak value of 1.7x10(9)/l 5 months after the beginning of treatment with fludarabine. A thorough investigation for other causes of eosinophilia was negative and the eosinophilia subsided after the completion of the treatment.
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