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Updated: Sep 16, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
A case of multidrug-resistant (MDR) tuberculosis with collapse of the left lung after hemoptysis
Yoshiyuki Abe1, Satoshi Kurita, Yasuyuki Ohkubo
1Department of Respiratory Disease, National Sanatorium Kanagawa Hospital, 666-1, Ochiai, Hadano-shi, Kanagawa 259-8585, Japan. abey@kanagawa.hosp.go.jp
Abstract:
An 82-year-old female was admitted to our hospital with multidrug-resistant (MDR) tuberculosis, defined as resistance to both isoniazid and rifampicin. Chest X-ray showed massive infiltrates with a large cavitary lesions in the left lung field. No antituberculous agents were useful in improving her clinical condition and at 6th months after admission, she exhibited sudden onset of massive hemoptysis, which was successfully treated by bronchial artery embolization. After hemoptysis, her chest X-ray showed collapse of the left lung and computed tomography showed a coagula-like shadow in the left main bronchus, and sputum examination revealed no Mycobacterium tuberculosis colonies. The patient was discharged 5 months after the onset of hemoptysis.
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