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Dyspepsia: initial evaluation and treatment.

Brian L Erstad1

  • 1Department of Pharmacy Practice & Science, College of Pharmacy, University of Arizona, Tucson 85721-0207, USA. erstad@pharmacy.arizona.edu

Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|May 28, 2002
PubMed
Summary
This summary is machine-generated.

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Dyspepsia, or indigestion, can often be managed with over-the-counter medications. However, pharmacists must recognize serious symptoms that warrant physician referral for accurate diagnosis and treatment.

Area of Science:

  • Gastroenterology
  • Pharmacology
  • Internal Medicine

Background:

  • Dyspepsia is a prevalent gastrointestinal (GI) complaint.
  • It encompasses symptoms like indigestion and upset stomach without a clear organic cause.
  • Identifying underlying serious conditions is crucial for appropriate patient management.

Purpose of the Study:

  • To establish guidelines for the initial assessment and treatment of dyspepsia.
  • To differentiate functional dyspepsia from conditions requiring medical referral.
  • To inform pharmacists about red flag symptoms associated with serious GI disorders.

Main Methods:

  • A comprehensive literature search was conducted using MEDLINE and other sources.
  • Studies published in English from 1966 to June 2001 were included.

Related Experiment Videos

  • Textbooks and bibliographies were also reviewed to gather information on diagnosis and management.

    • Main Results:

    • Functional dyspepsia can be alleviated by medications such as antacids, H2RAs, PPIs, and promotility agents.
    • It is essential to avoid masking symptoms of severe conditions, which could delay diagnosis and treatment.
    • Peptic ulcer disease and gastroesophageal reflux disease each represent approximately 20% of dyspepsia cases.
    • Gastric cancer is a consideration in patients over 45, particularly the elderly.

    Conclusions:

    • Nonprescription drugs can effectively treat functional dyspepsia.
    • Pharmacists play a key role in identifying patients who need physician referral.
    • Awareness of warning signs is critical for timely diagnosis and management of complex GI diseases.