Incisionless in-office castration using a veterinary castration device (Burdizzo clamp)
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Updated: Oct 1, 2026

Murine Orchiectomy and Ovariectomy to Reduce Sex Hormone Production
Published on: November 17, 2023
Michael E Herzog1, Richard A Santucci
1Department of Urology, Wayne State University School of Medicine, Detroit, Michigan 48167, USA.
Abstract:
Nonoperative ablation of the testicular artery has been described in animals using the Burdizzo clamp, but not in humans. We report a case of incisionless castration performed using local anesthesia, in a transsexual who wished to avoid the pain, expense, and scar associated with the open procedure. The Burdizzo clamp crushed the spermatic cord bilaterally, and the testis was allowed to atrophy. The soft-tissue damage was minimal, and the serum testosterone fell to castrate levels. This method has proved useful for castration in a transgender patient, but could also be used for castration in patients with advanced prostate cancer.

