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Related Experiment Videos

Dark-without-pressure fundus lesions.

K C Nagpal, M F Goldberg, G Asdourian

    The British Journal of Ophthalmology
    |September 1, 1975
    PubMed
    Summary
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    New fundus lesions in Black patients, termed dark-without-pressure, were observed. These transient, dark brown areas may be linked to sickle cell disease or hypertension.

    Area of Science:

    • Ophthalmology
    • Retinal Imaging
    • Vascular Biology

    Background:

    • Fundus examination is crucial for diagnosing various ocular conditions.
    • Understanding retinal variations in different ethnicities is important for accurate diagnosis.
    • Sickle cell haemoglobinopathies and systemic hypertension can manifest with distinct fundus findings.

    Observation:

    • Seven Black patients presented with dark brown, homogeneous geographical fundus areas.
    • These lesions were observed in the posterior pole or mid-periphery of the retina.
    • The lesions were flat, uniform in color, and transient, often resolving without residue.

    Findings:

    • Six cases were associated with sickle cell haemoglobinopathies.
    • One case was associated with systemic hypertension.

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  • The etiology of these dark-without-pressure lesions remains unknown.

    • Implications:

    • These findings describe a novel fundus finding, potentially aiding in the early detection of related systemic conditions.
    • The term "dark-without-pressure" is proposed by analogy to "white-without-pressure" lesions.
    • Further research is needed to elucidate the pathogenesis and clinical significance of these transient retinal areas.