Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lichen sclerosus. A review.

Y W Wong1, J Powell, M A Oxon

  • 1Department of Dermatology, The Churchill Old Road, Headington, Oxford, UK.

Minerva Medica
|May 29, 2002
PubMed
Summary

Lichen sclerosus is a chronic inflammatory skin condition affecting any age or sex, causing physical and psychological distress. Potent topical steroids are the primary treatment, with ongoing research into future targeted interventions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

European S2k guidelines on management of autoimmune blistering diseases in children and adolescents.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same author

One-hundred-fifteen consecutive bladder exstrophies successfully closed in a single nationally commissioned centre.

Journal of pediatric urology·2025
Same author

Extended-spectrum β-lactamase-producing bacteria from hospital wastewater pipes: isolation, characterization and biofilm control using common disinfectants.

The Journal of hospital infection·2024
Same author

More than just the gene: investigating expression using a non-native plasmid and host and its impact on resistance conferred by β-lactamase OXA-58 isolated from a hospital wastewater microbiome.

Letters in applied microbiology·2024

Area of Science:

  • Dermatology
  • Inflammatory skin conditions

Background:

  • Lichen sclerosus is a chronic inflammatory skin disease with significant physical and psychological impact.
  • It commonly affects the anogenital region, primarily in women, but can occur anywhere on the skin in any sex or age group.
  • Symptoms include itching, soreness, urinary dysfunction, sexual problems, and an increased risk of squamous cell carcinoma.

Purpose of the Study:

  • To provide a comprehensive overview of lichen sclerosus.
  • To discuss the known associations and potential etiological factors.
  • To outline current treatment strategies and future research directions.

Main Methods:

  • Literature review of lichen sclerosus.
  • Summary of clinical presentation and risk factors.
  • Overview of established and emerging therapeutic approaches.

Main Results:

  • Lichen sclerosus presents with diverse symptoms and affects various populations.
  • Genetic factors and autoimmune associations are recognized, though etiology remains unclear.
  • Potent topical corticosteroids are the primary treatment, with surgery reserved for scarring complications.

Conclusions:

  • Lichen sclerosus requires long-term follow-up due to potential complications like cancer.
  • Understanding the disease pathogenesis is crucial for developing future targeted therapies.
  • Current management focuses on symptom relief and preventing long-term sequelae.

Related Experiment Videos