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Premenstrual syndrome
1Reproductive Endocrinology and Infertility Program, Department of Obstetrics and Gynecology, University of Western Ontario, London, ON, Canada.
Minerva Ginecologica
|May 29, 2002
Summary
Premenstrual syndrome (PMS) impacts millions of women. This review explores current theories and treatments for PMS, focusing on the interplay between sex hormones and neurotransmitters.
Area of Science:
- Gynecology
- Neuroscience
- Psychiatry
Background:
- Premenstrual syndrome (PMS) significantly affects women's quality of life.
- The complex and varied symptoms of PMS, including affective and somatic issues, pose challenges for diagnosis and treatment.
- The exact cause of PMS remains unclear, but imbalances in sex hormones and central neurotransmitters are suspected.
Purpose of the Study:
- To review the most accepted theories regarding the origin of PMS.
- To summarize current treatment options for PMS.
- To base the review on evidence from well-designed clinical trials.
Main Methods:
- Literature review of studies on PMS pathophysiology and treatment.
- Analysis of data from rigorously designed clinical trials.
- Synthesis of current understanding of PMS etiology and management.
Main Results:
- The review consolidates leading theories on PMS development.
- It presents an overview of established and emerging PMS treatments.
- Evidence from high-quality trials informs the summary of treatments.
Conclusions:
- Understanding PMS pathophysiology is crucial for effective treatment.
- Current treatments aim to manage the hormonal and neurotransmitter imbalances implicated in PMS.
- Further research based on robust trials is needed to refine PMS management strategies.