Prosthetic infections

A Matarazzo1, O Sassi, A Florio

  • 1Cattedra di Chirurgia Vascolare, Seconda Università degli Studi, Naples, Italy.

Abstract

Insights

Vascular graft infections are serious complications, but treatment outcomes have improved with better materials and surgical care. Early, localized infections may allow for prosthesis preservation through open local treatment.

Area of Science:

  • Vascular Surgery
  • Infectious Diseases
  • Prosthetic Materials

Background:

  • Vascular graft infections pose significant challenges in surgical practice.
  • Understanding etiopathology, diagnosis, and treatment is crucial.
  • Key concerns include causative microorganisms, anastomotic pseudoaneurysm, and aortoenteric fistula.

Purpose of the Study:

  • To review current trends in vascular-graft infection management.
  • To analyze the outcomes of prosthetic infections.

Main Methods:

  • A retrospective case study analyzing 19 prosthetic infections from 520 implant operations between 1990 and 1999.

Main Results:

  • Out of 19 cases, 11 treatments were successful.
  • Seven patients required amputation.
  • One case resulted in a decrease in condition.

Conclusions:

  • Treatment results have improved due to refined protocols, infection-resistant materials, and enhanced aseptic techniques.
  • Graft infection remains a severe complication requiring aggressive treatment, often involving prosthesis removal.
  • Open local treatment is a viable option for select, localized infections, potentially preserving the prosthesis.

Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...