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Night-to-night variability of polysomnography in children with suspected obstructive sleep apnea
Eliot S Katz1, Mary G Greene, Kathryn A Carson
1Eudowood Divison of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Insights
A single night of polysomnography is adequate for diagnosing obstructive sleep apnea syndrome (OSAS) in children. This study found minimal night-to-night variability, suggesting one test reliably measures pediatric OSAS.
Area of Science:
- Pediatric Sleep Medicine
- Respiratory Physiology
Background:
- Obstructive sleep apnea syndrome (OSAS) is common in children with sleep-disordered breathing.
- Assessing OSAS severity often relies on polysomnography (PSG).
- Concerns exist regarding night-to-night variability in PSG results.
Purpose of the Study:
- To evaluate the reliability of a single PSG night for diagnosing pediatric OSAS.
- To determine the extent of night-to-night variability in key PSG parameters.
Main Methods:
- Prospective study of 30 children (1.6-11.3 years) with snoring.
- Two nocturnal PSG recordings were performed 7-27 days apart.
- Respiratory and sleep parameters were analyzed for night-to-night differences.
Main Results:
- No significant differences were found in apnea index, apnea/hypopnea index, or oxygen saturation between nights.
- Sleep efficiency, arousal index, and REM/slow wave sleep percentages were stable.
- The clinical diagnosis of OSAS remained consistent for all children.
Conclusions:
- Pediatric polysomnography exhibits minimal clinically significant night-to-night variability.
- A single PSG night is a reliable measure for diagnosing OSAS in children with sleep-disordered breathing symptoms.
- No first-night effect was observed in this pediatric cohort.
Objectives:
To determine whether a single polysomnographic night was a valid measure of obstructive sleep apnea syndrome (OSAS) in children with symptoms of sleep-disordered breathing.
Study Design:
The night-to-night variability of respiratory and sleep parameters was measured prospectively in 30 snoring children aged 1.6 to 11.3 years (mean +/- SD, 4.1 +/- 2) by using 2 nocturnal polysomnograms performed 7 to 27 days apart (14 +/- 5 days).
Results:
The mean of the respiratory variables including apnea index, apnea/hypopnea index, arterial oxygen saturation, and end-tidal partial pressure of carbon dioxide were not significantly different from night to night. Among the sleep parameters, there was no significant night-to-night difference in sleep efficiency, arousal index, percent rapid eye movement, or percent of slow wave sleep. Only the percentage of stage 2 was significantly different between the nights. The polysomnographic clinical diagnosis remained the same on both nights for all children, although the disease severity differed slightly in 2 patients.
Conclusions:
There is little clinically significant night-to-night variability in pediatric polysomnography, and no first-night effect. These data suggest that a single polysomnographic night is an adequate measure of the OSAS in children with symptoms of sleep-disordered breathing.
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